Sevilla currently foot Group B but are just three points off second-placed PSV with two games to play. The home side have been in poor form of late, though, winning just one of their last 11 matches, that coming at lower league side CD Quintanar in the Copa Del Rey.
By comparison, PSV have been in excellent form, and come into Wednesday's game unbeaten in 12, winning two. Both draws in that run did come in the Champions League, however.
PSV have won four of their last five on the road and may just edge out Sevilla.